Assistant Professor
Inorganic and Bioinorganic Chemistry

DH 281
(408) 924-5283
lionel.cheruzel@sjsu.edu
Research Group Page

Education

Postdoctoral Fellow 2006-2009, California Institute of Technology (with Harry B. Gray)
Ph.D. 2004, University of Louisville, Kentucky (with Robert M. Buchanan)
French Engineer Diploma 2000, Montpellier, France.

Courses Taught

Inorganic Chemistry
Bioinorganic Chemistry
General Chemistry I
General Chemistry II

Research Interests

• Development of hybrid P450 enzymes;
• Photocatalytic chemistry.

Selected Publications

• Tran, N.H.; Huynh, N.; Chavez, G.; Nguyen, A.; Dwaraknath, S.; Nguyen, T. A.; Nguyen, M.; Cheruzel, L.E. "A series of hybrid P450 BM3 enzymes with different catalytic activity in the light-initiated hydroxylation of lauric acid" 2012, In press.
• Tran, N.H.; Huynh, N.; Bui, T.; Nguyen, Y.; Huynh, Y.; Cooper, Cheruzel, L.E. "Light-initiated hydroxylation of lauric acid using hybrid P450 BM3 enzymes" Chem. Commun.2011, 47 11936-11938.
• Cheruzel, L.E.; Cui, J.L.; Mashuta, M.S.; Grapperhaus, C.A.; Buchanan, R.M. "N-(2-formyl-1-methylimidazol-4-yl)-2,2-dimethylpropan-amide: a versatile reagent for preparing imidazole-amine
  ligands with variable second-coordination spheres" Tetrahedron Letters2011, 52 4771-4774.
• Ener, M.; Lee, Y.-T.; Winkler, J.R.; Gray, H.B.; Cheruzel, L.E. "Photooxidation of Cytochrome P450-BM3" Proc. Natl. Acad. Sci. USA2010,107, 18783-18786.
• Langley, D.B.; Brown, D.E.; Cheruzel, L.E.; Contakes, S.M.; Duff, A.P.; Hilmer, K.M.; Dooley, D.M.; Gray, H.B.; Guss, J.M.; Freeman, H.C. “Enantiomer-specific binding of ruthenium(II) molecular wires by the amine oxidase of Arthrobacter globiformis” J. Am. Chem. Soc.2008,130, 8069-8078.
• Cheruzel, L.E.; Cecil, M.R.; Edison, S.E.; Mashuta, M.S.; Baldwin, M.J.; Buchanan, R.M. “Structural and spectroscopic characterization of copper(II) complexes of a new bis-amide functionalized imidazole tripod and evidence for the formation of a mononuclear end-on Cu-OOH species” Inorg. Chem.2006,45, 3191-3202.
• Cheruzel, L.E., Mashuta, M.S.; Buchanan, R.M. “A supramolecular assembly of side-by-side polyimidazole tripod coils stabilized by π-π stacking and unique boric acid templated hydrogen-bonding interactions” Chem. Commun.2005, 17, 2223-2225.
• Cheruzel, L.E., Pometun, M.S.; Cecil, M.R.; Mashuta, M.S.; Wittebort, R.J.; Buchanan, R.M. “Structures and solid-state dynamics of one-dimensional water chains stabilized by imidazole channels” Angew. Chem. Int. Ed.,2003, 42, 5452-5456.