Professor
Analytical Chemistry

DH 501
(408) 924-4950
joseph.pesek@sjsu.edu

Pesek Group Page

Education

B.S., Chemistry, University of Illinois, 1966
Ph.D., Analytical Chemistry, UCLA, 1970
Postdoctoral Fellow, UCLA, 1970-1971

Courses Taught

Quantitative Analysis
Instrumental Analysis
Current Topics in Analytical Chemistry

Research Interests

• Separation methods including high performance liquid chromatography (HPLC), LCMS, capillary electrophoresis, capillary electrochromatography and microfluidic chips.
• Chemical modification of surfaces used in separation methods.
• Metabolomics and proteomics.

Selected Publications

• “A New Approach to Bioanalysis: Aqueous Normal Phase Chromatography with Silica Hydride Stationary Phases,” J.J. Pesek, M.T. Matyska, Bioanalysis, 4 (2012) 845-853. 
• “Analysis of cycloserine and related compounds using aqueous normal phase chromatography/mass spectrometry”, J.J. Pesek, M.T. Matyska, A. Dang, J. Pharm. Biomed. Anal., 64-65 (2012) 72-76.
• “Simultaneous separation of hydrophobic and hydrophilic peptides with a silica hydride stationary phase using aqueous normal phase conditions”, R.I. Boysen, Y. Yang, J. Chowdhury, M.T. Matyska, J.J. Pesek, M.T.W. Hearn, J. Chromatogr. A,. 1218 (2011) 8021-8026.
• “Open Tubular Capillary Electrochromatography of Small Polar Molecules using Etched, Chemically Modified Capillaries”, J.J. Pesek, M.T. Matyska, M. Nshanian, Electrophoresis, 32 (2011) 1728-1734.
• "Aqueous Normal Phase (ANP) Retention of Nucleotides on Silica Hydride-Based Columns. Method Development Strategies for Analytes Relevant in Clinical Analysis”, J.J. Pesek, M.T. Matyska, J. Duley, M. Zamzami, S.M. Fischer, J. Sep. Sci., 33 (2010) 930-938. 
• “1H HR/MAS NMR in the suspended state: Molecular recognition processes in liquid chromatography between steroids and a silica hydride-based cholesterol phase”, V. Freibolin, M. P. Bayer, M.T. Matyska, J. J. Pesek, K, Albert, J. Sep. Sci. 32 (2009) 1722-1728.
• “Aqueous normal-phase retention of nucleotides on silica hydride columns”, J.J. Pesek, M.T. Matyska, M.T.W. Hearn, R.I. Boysen, J. Chromatogr. A, 1216, (2009) 1140-1146.
• “Our Favorite Materials: Silica Hydride Stationary Phases”, J.J. Pesek, M.T. Matyska, J. Sep. Sci., 32 (2009) 3999-4011.
• “Analysis of hydrophilic metabolites by high-performance liquid chromatography - mass spectrometry using a silica hydride-based stationary phase”, J.J. Pesek, M.T. Matyska, S.M. Fischer, T.R. Sana, J. Chromatogr. A, 1204 (2008) 48-55.