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Welcome to The Cheruzel Research Group Website
CHERUZEL WINS EARLY CAREER INVESTIGATOR AWARD
Chemistry professor Lionel Cheruzel has been named one of two Early Career Investigator Award winners by the San Jose State University Research Foundation. Cheruzel (pictured with research student Ngoc-Han Tran) was recognized for excellence in the areas of research, scholarship, or creative activity.
Cheruzel's Research featured at SJSU event
On Thursday October 18 President Mohammad Qayoumi co-hosted an event billed as “A Celebration of SJSU Sponsored Research”. One of two featured speakers was Professor Lionel Cheruzel, who recently won the Early Career Investigator Award.
Fall 2012 Chem 1A students enjoying Chemistry
A group of kinesiology students wearing "I LOVE CHEMISTRY" T-Shirt for final Chem 1A exam (Fall 2012).
Christmas 2012 Lab Potluck
Celebration of the end of semester, traditional lab potluck and group picture
Welcome to The Cheruzel Research Group Website
The specific and selective oxidation of an unactivated C-H bond remains one of the most challenging reactions in organic chemistry. Cytochrome P450 is a unique superfamily of heme-thiolate enzymes that catalyze the insertion of an oxygen atom, derived from molecular dioxygen, into a C-H bond of a variety of organic substrates, often with high degrees of regio- and stereoselectivity. Recent interests in these proteins arise from the desire to harness their synthetic potential for biotechnological applications.
Our laboratory focuses on developing hybrid P450 biocatalysts capable of the selective oxidation of organic substrate C-H bonds upon light activation. The hybrid enzymes consist of a photosensitizer covalently attached to P450 heme domains.
