23) V. Sosa, M. Melkie, C. Sulca, J. Li, L. Tang, J. Li, J. Faris, T. Banh, M. Kato, L.  Cheruzel* Selective light-driven chemoenzymatic trifluoromethylation/hydroxylation of substituted arenes, ACS Catalysis, 2018, ASAP.

BBA Graphical Abstract 

22) H. Shalan, M. Kato, L. Cheruzel, Keeping the Spotlight on Cytochrome P450,Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics2018, 1866, 80-87.


Inorganic Chemistry Graphical Abstract 

21) , , , , orrelating the para-Substituent Effects on Ru(II)-Polypyridine Photophysical Properties and on the Corresponding Hybrid P450 BM3 Enzymes Photocatalytic Activity 

BBA 2016 Abstract 

20) JessicaSpradlin, DianaLee, SruthiMahadevan, MavishMahomed, LawrenceTang, QuanLam, AlexanderColbert, Oliver S.Shafaat, DavidGoodin, MarcoKloos, MalloryKato, Lionel E.Cheruzel Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics20161864 (12), 1732-1738 Insights into an efficient light-driven hybrid P450 BM3 enzyme from crystallographic, spectroscopic and biochemical studies


BBA Proteomics Graphical Abstract 

19) Q. Lam, A. Cortez, T. T. Nguyen, M. Kato, L. Cheruzel, J Inorg. Biochem., 158, 201686-91 Chromogenic nitrophenolate-based substrates for light-driven hybrid P450 BM3 enzyme assay



18)MalloryKato, QuanLam, MeghanaBhandarkar, TamBanh, JeremiahHeredia, AndrewU, LionelCheruzel Comptes Rendus Chimie201720 (3), 237-242 Selective C–H bond functionalization with light-driven P450 biocatalysts 





17) QuanLam, MalloryKato, LionelCheruzel Biochimica et Biophysica Acta (BBA) - Bioenergetics20161857 (5), 589-597 Ru(II)-diimine functionalized metalloproteins: From electron transfer studies to light-driven biocatalysis

 Abstract Image BioOrg Med Chem

16) M. Kato, D. Nguyen, M. Gonzalez, A. Cortez, S. Mullen, L. Cheruzel.* Regio- and stereoselective hydroxylation of 10-undecenoic acid with a light-driven P450 BM3 biocatalysts yielding a valuable synthon for natural product synthesis. BioOrg. Med. Chem.2014, 22, 5687-5691. 

15) S. Dwaraknath, N.-H. Tran, T. Dao, A. Colbert, S. Mullen, A. Nguyen, A. Cortez, L. E. Cheruzel* A facile and versatile methodology for cysteine specific labeling of proteins with octahedral polypyridyl d6 metal complexes. J. Inorg. Biochem., 2014, 136, 154-160.

14) N.-H. Tran, D. Nguyen, S. Dwaraknath, S. Mahadevan, G. Chavez, A. Nguyen, T. Dao, S. Mullen, T.-A. Nguyen, L. E. Cheruzel* An Efficient Light-driven P450 BM3 Biocatalyst. J. Am. Chem. Soc.2013,135, 14484-14487

13) J. G. Rohan, Y. R. Citron, A. C. Durrell, L. E. Cheruzel*, H. B. Gray, R. H. Grubbs, M. Humayun, K. L. Engisch, V. Pikov, R. H. Chow Light-Triggered Modulation of Cellular Electrical Activity by Ruthenium Diimine Nanoswitches. ACS Chem. Neurosci.20134, 585-593.

12) N.H. Tran, N. Huynh, G. Chavez, A. Nguyen, S. Dwaraknath, T.A Nguyen, M. Nguyen, L. Cheruzel* A series of hybrid P450 BM3 enzymes with different catalytic activity in the light-initiated hydroxylation of lauric acid. J. Inorg. Biochem., 2012, 115, 50-57.


11) N.H. Tran, N. Huynh, T. Bui, Y. Nguyen, P. Huynh, M.E. Cooper, L. E. Cheruzel* Light-initiated hydroxylation of lauric acid using hybrid P450 BM3 enzymes. Chem. Commun. 2011, 47 11936-11938.

10) Cheruzel, L. E.; Cui, J. L.; Mashuta, M. S.; Grapperhaus, C.A.; Buchanan, R. M. N-(2-formyl-1-methylimidazol-4-yl)-2,2-dimethylpropanamide: a versatile reagent for preparing imidazole-amine ligands with variable second-coordination spheres Tetrahedron Letters 201152 4771-4774.

9) M. Ener; Y.-T. Lee; J. R. Winkler; H. B., Gray; L. E. Cheruzel* Photooxidation of cytochrome P450-BM3.Proc. Natl. Acad. Sci. USA2010, 107, 18783-18786.


8) Langley, D. B.; Brown, D. E.; Cheruzel, L. E.; Contakes, S. M.; Duff, A. P.; Hilmer, K. M.; Dooley, D. M.; Gray, H. B.; Guss, J. M.; Freeman, H. C. Enantiomer-specific binding of ruthenium(II) molecular wires by the amine oxidase of Arthrobacter globiformis J. Am. Chem. Soc., 2008, 130, 8069-8078. 

7) Edison, S.E.; Conklin, S.D.; Kaval N.; Cheruzel, L. E.; Krause, J.A.; Seliskar, C. J.; Heineman W. R.; Buchanan R. M.; Baldwin, M. J. Inorg. Chim. Acta, 2008, 361, 947-955. “Spectroscopic characterization of a Ni-organic radical intermediate in the aerobic oxidation of methanol catalyzed by a Ni(II)( polyoximate) complex”

6) Cheruzel, L. E.; Cecil, M. R.; Edison, S. E.; Mashuta, M. S.; Baldwin, M. J.; Buchanan, R. M. Inorg. Chem.,2006, 45, 3191-3202. “Structural and spectroscopic characterization of copper(II) complexes of a new bis-amide functionalized imidazole tripod and evidence for the formation of a mononuclear end-on Cu-OOH species”

5) Cheruzel, L. E; Mashuta, M. S.; Buchanan, R. M. Chem. Commun.,2005, 17, 2223-2225. “A supramolecular assembly of side-by-side polyimidazole tripod coils stabilized by ¹-¹ stacking and unique boric acid templated hydrogen-bonding interactions”

4) Mashuta, M. S.; Cheruzel, L. E Buchanan, R. M. Acta Cryst. C2005, 61, O361-O362. “5,10-dihydroxy-5H,10H-diimidazo[1,2-a : 1',2'-d]pyrazine”

3) Cheruzel, L. E Pometun, M. S.; Cecil, M. R.; Mashuta, M. S.; Wittebort, R. J.; Buchanan, R. M. Angew. Chem. Int. Ed.,2003, 42, 5452-5456. “Structures and solid-state dynamics of one-dimensional water chains stabilized by imidazole channels”

2) Cheruzel, L. E; Wang, J. P.; Mashuta, M. S.; Buchanan, R. M. Structure and properties of an Fe(III) complex containing a novel amide functionalized polyimidazole ligand Chem. Comm.2002, 2166-2167. 

1) Mashuta, M. S.; Cheruzel, L. E Buchanan, R. M. Tris[(1-methylimidazol-2-yl)methyl]-amine-boric acid (1/1) Acta Cryst. C. 2002, 58, O629-O631.