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Adrian Rodriguez, Ph.D.
Associate Professor
Department of Biological Sciences
San José State University
Department of Biological Sciences
One Washington Square
San José, CA 95192-0100
Duncan Hall, Room 535
Telephone: (408) 924-4846
FAX: (408) 924-4840
E-mail: rodriga@email.sjsu.edu
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Teaching-Courses Taught:
- Biol 66, Human Physiology
- Biol 124/125, Mammalian Physiology
- Biol 137, Introduction to Toxicology
- Biol 202, Graduate Studies in Biology
- Biol 223, Radiation Biology
- Biol 255P, Advanced Topics in Biology - Physiology
- Nucs 121S, Radiation Safety
Education
Ph.D. Oregon State University, Corvallis, OR; Radiation Biology/Physiology, 1975
M.A. San Jose State College, San Jose, CA; Biological Sciences, 1969
B.A. San Jose State College, San Jose, CA; Biological Sciences, 1967
Professional Experience:
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Fall 1991-
present
Spring 1991
1978-1990
1976-1978
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Associate Professor, Department of Biological Sciences, San Jose
State University, San Jose, Ca.
Full time temporary teaching appointment - Department of Biological
Sciences, San Jose State University, San Jose, CA. Lectured in Radiation
Biology (Chem. 128) and Anatomy and Physiology Lab. (Biology 54 & Biol. 66)
Staff Scientist 2/Physiologist - Division of Cell and Molecular Biology,
Lawrence Berkeley Laboratory, University of California, Berkeley, CA.
Postdoctoral Fellowship - National Research Service Award in Radiation
Biophysics, Division of Medical Physics, University of California, Berkeley, CA.
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Research:
Cellular radiation biology and Toxicology. Assessing the genotoxicity of ionizing
radiation and oxidizing agents resulting in genomic instability, cell transformation
and mutagenesis. Assessment of genotoxicity by induction of micronuclei in exposed
cells and induction of 8-oxo-guanine in DNA. Assessment of the efficacy of antioxidants
in reducing the effects of ionizing and oxidizing agents.
Recent Abstracts and Papers:
A. Rodriguez, E.L. Alpen, and P. Powers-Risius. The RBE-LET relationship for
rodent intestinal crypt cell survival, testes weight loss and multicellular spheroid
cell survival after heavy ion irradiation. Radiat. Res. 132, 184-192 (1992)
A. Rodriguez, R.P. Levy, and J.I. Fabrikant. Experimental central nervous system
injury following charged-particle irradiation. in Radiation Injury to the Nervous
System, Raven Press, New York (eds. P.H. Gutin, S.A. Leibel, and G.E. Sheline).
pp 149-182, 1991.
M. S. Mendonca, A. Rodriguez, and E.L. Alpen. Differential expression of potentially
lethal damage in exponentially growing and quiescent 9L cells. Radiat. Res. 122, 38-43
(1990).
M.S. Mendonca, A. Rodriguez, and E.L. Alpen. Quiescence in 9L cells and correlation
with radiosensitivity and PLD repair. Radiat. Res. 117, 443-447 (1989).
C.S. Parkins, A. Rodriguez, and E.L. Alpen. Radiation damage to glucose concentrating
capacity and cell survival in kidney tubule cells: effects of fractionation. Int. J. Radiat.
Biol. 55, 15-26 (1989).
A. Rodriguez, E.L. Alpen, and R.J. DeGuzman. Recovery from potentially lethal damage
and recruitment time of noncycling clonogenic cells in 9L confluent monolayers and
spheroids. Radiat. Res. 114, 515-527 (1988).
C.A. Tobias, E.A. Blakely, E.L. Alpen, J.R. Castro, E.J. Ainsworth, S.B. Curtis, F.Q. Ngo,
A. Rodriguez, R.J. Roots, T. Tenforde, and T.C.H. Yang. Molecular and cellular radiobiology
of heavy ions. Int. J. Radiat. Oncol. Biol. Phys. 8, 2109-2120 (1982).
A. Rodriguez and E.L. Alpen. Feeder cells and cell survival in spheroids and monolayers.
Int. J. Radiat. Res. 41, 111-117 (1982).
A. Rodriguez and E.L. Alpen. Cell survival in spheroids with heavy-ion beams. Radiat.
Res. 85, 24-37 (1981).
Abstracts:
Randal Mihara and Adrian Rodriguez (Department of Biological Sciences, SJSU) Effects of
Ionizing Radiation on the Expression of The Gene Encoding the Na+-Glucose Cotransporter
(SGLT1) in LLC-PK1 Porcine Kidney Cells. In: Proceedings of the Spring Meeting of the
Genetic and Environmental Toxicology Association (GETA) cosponsored by the NorCal
Society of Toxicology and The NorCal Society for Risk Analysis. At the Oakland Museum
of California, June 3, 1997.
L. David Waterbury1, Adrian Rodriguez2, and Laurie Zagazeta1,2 (1Centaur Pharmaceuticals,
Sunnyvale, CA; 2Department of Biological Sciences, SJSU). The Effects of N-Tert-Butyl-?-
Phenylnitrone (PBN) on Leukocytes and Survival in Irradiated Mice. In: Proceedings of
the Spring Meeting of the Genetic and Environmental Toxicology Association (GETA) cosponsored
by the NorCal Society of Toxicology and The NorCal Society for Risk Analysis. At the Oakland
Museum of California, June 3, 1997.
Albert V. Bystritskii and Adrian Rodriguez (Department of Biological Sciences, SJSU).
Radiation Damage to the Sixth Abdominal Ganglion of the Crayfish, Procambarus clarkii.
Proceedings of the Pacific Division, American Association for the Advancement of Science
15 (1), 36, 1996.
Mihara, Randal and Rodriguez, Adrian (Department of Biological Sciences, SJSU). Quantitative
Analysis of the Primary transcript (mRNA) of the SGLT1 Gene in LLC-PK1 Porcine Kidney Cells.
Proceedings of the Pacific Division, American Association for the Advancement of Science 15 (1), 47,
1996.
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