Review Questions for Chapter 10 

1. What does the French word trier mean? 
2. What distinguishes an experiment from an observational study?
3. Distinguish between clinical trials, field trials, and community trials. 
4. Define each of these words: randomized controlled double-blinded trial.
5. Was Lind's historical study of scurvy (e.g., Table 10.1, p. 183) a randomized trial? 
6. Was Parés study of the treatment of wounds (pp. 183 - 184) a true an experiment?
7. Why is it important to observe the control group under the same conditions as the treatment group?
8. This phrase is used to refer to improvement due the feeling of being observed.
9. What is the placebo effect?
10. How does randomization reduce confounding?
11. What are admissibility criteria? How do admissibility criteria encourage comparability?
12. List the three guidelines of  the Belmont Report (p. 187).
13. What is equipoise?
14. What is  informed consent?
15. What is an IRB?
16. How does intention-to-treat analysis differ from treatment-received analysis?
17. Provide a synonym for intention-to-treat analysis. 

Last update: 11/23/2008

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