Chemical Biology Research Group Members
Assistant Professor, Biochemistry
Protein biochemistry and bacterial genetics to study molecular chaperones as potential antibacterial targets
The Carroll lab studies the effects of the cellular environment on protein misfolding, aggregation, and amyloid formation. We are also interested in how the cellular protein homeostasis network, especially ubiquitin, responds to different amyloidosis.
Computational methods development using molecular simulations and machine learning to study configurational dynamics in biomolecules, molecular self-assembly, and reaction dynamics.
Computational/theoretical methods to characterize entropy and related effects in proteins and RNA; drug design that includes potential anti-HIV agents.
Synthesis and investigation of anti-quorum sensing and anti-virulence compounds in bacteria.
Lanthanides, complexes, circularly polarized luminescence, chirality, thermodynamics, and spectroscopy.
Protein conformational dynamics, protein-protein interactions, enzyme specificty.